Plant Transcription Factor Database
Previous version: v3.0
Brassica napus
NF-YA Family
Species TF ID Description
GSBRNA2T00003328001NF-YA family protein
GSBRNA2T00003651001NF-YA family protein
GSBRNA2T00005976001NF-YA family protein
GSBRNA2T00009255001NF-YA family protein
GSBRNA2T00011831001NF-YA family protein
GSBRNA2T00016247001NF-YA family protein
GSBRNA2T00019851001NF-YA family protein
GSBRNA2T00031185001NF-YA family protein
GSBRNA2T00034786001NF-YA family protein
GSBRNA2T00045617001NF-YA family protein
GSBRNA2T00046328001NF-YA family protein
GSBRNA2T00050238001NF-YA family protein
GSBRNA2T00051978001NF-YA family protein
GSBRNA2T00053729001NF-YA family protein
GSBRNA2T00054017001NF-YA family protein
GSBRNA2T00063860001NF-YA family protein
GSBRNA2T00067245001NF-YA family protein
GSBRNA2T00084442001NF-YA family protein
GSBRNA2T00088675001NF-YA family protein
GSBRNA2T00092506001NF-YA family protein
GSBRNA2T00099533001NF-YA family protein
GSBRNA2T00102603001NF-YA family protein
GSBRNA2T00103373001NF-YA family protein
GSBRNA2T00103376001NF-YA family protein
GSBRNA2T00104205001NF-YA family protein
GSBRNA2T00107041001NF-YA family protein
GSBRNA2T00111892001NF-YA family protein
GSBRNA2T00113750001NF-YA family protein
GSBRNA2T00114112001NF-YA family protein
GSBRNA2T00119998001NF-YA family protein
GSBRNA2T00122364001NF-YA family protein
GSBRNA2T00129889001NF-YA family protein
GSBRNA2T00136206001NF-YA family protein
GSBRNA2T00136782001NF-YA family protein
GSBRNA2T00137180001NF-YA family protein
GSBRNA2T00137319001NF-YA family protein
GSBRNA2T00140306001NF-YA family protein
GSBRNA2T00141371001NF-YA family protein
GSBRNA2T00143425001NF-YA family protein
GSBRNA2T00151958001NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982